Clin2
NCT06543576Possibly a fitRecruiting

Radiation and drug therapy for stage IVB cervical cancer

Cervical AdenocarcinomaCervical Adenosquamous CarcinomaCervical Squamous Cell CarcinomaStage IVB Cervical Cancer American Joint Committee on Cancer (AJCC) v8

Treatments studied

Part of Cancer, Women’s health & pregnancy clinical trials.

This trial tests combining external and internal radiation with chemotherapy and immunotherapy for stage IVB cervical cancer that has not been treated before. The goal is to see if this approach can help shrink tumors and improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
35 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be at least 18 years old with stage IVB cervical cancer (a type that has spread beyond the cervix).
  • Your cancer must be a specific type (squamous cell, adenocarcinoma, or adenosquamous) and not have been treated with chemotherapy or radiation yet.
  • You need to have a tumor sample (from a biopsy or previous surgery) available for testing, and your PD-L1 score must be above 1.
  • You must be in good enough health to carry out daily activities (ECOG score 0 or 1) and have adequate blood counts and organ function.
  • You cannot have had certain prior treatments like immunotherapy targeting PD-1/PD-L1, a hysterectomy, or radiation for cervical cancer.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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