Immunotherapy with radiation for advanced cervical cancer
Treatments studied
Part of Cancer, Women’s health & pregnancy clinical trials.
This trial tests a drug called pembrolizumab (an immunotherapy that helps your immune system fight cancer) given along with a special type of radiation therapy (carbon-ion radiotherapy) for advanced cervical cancer. It aims to see if this combination is safe and effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with a specific type of cervical cancer (adenocarcinoma or adenosquamous carcinoma).
- Your cancer is at an advanced stage (IIA2, IIB, IIIA, IIIB, IIIC1r, or IVA).
- You have not had prior surgery, radiation, or systemic treatment for cervical cancer (except a minor procedure called conization).
- You have not previously received immunotherapy drugs like pembrolizumab or similar agents.
- You are generally in good health (able to carry out daily activities) and have adequate organ function.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests whether adding immunotherapy to chemotherapy, then giving chemotherapy together with radiation, works better for advanced cervical cancer. It aims to improve cancer control and help people live longer, without major safety issues.
This trial tests if giving the immunotherapy drug pembrolizumab before and after standard chemoradiation works better than the standard approach for people with high-risk cervical cancer that has spread locally.
This trial is testing a new immunotherapy drug (adebrelimab) given along with standard chemoradiation for advanced cervical cancer. The goal is to see if adding this drug improves treatment effectiveness.
This trial tests a new treatment that combines immunotherapy (drugs that help your immune system fight cancer) with carbon ion radiation (a precise type of radiation) for people with locally advanced cervical cancer that hasn't spread to other organs. The goal is to see if this combination is safe and effective.
This study tests a combination of two treatments: a drug called cadonilimab (a type of immunotherapy that helps your immune system fight cancer) and radiation therapy. It is for people with advanced cervical cancer who cannot receive the usual chemotherapy drug cisplatin, and aims to see if this combination is safe and effective.
This trial tests a new combination of short-course radiation, an immunotherapy drug called adebrelimab, and standard chemotherapy before surgery for locally advanced cervical cancer. It aims to see if this approach can shrink tumors more effectively.
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