Random biopsies in inflammatory bowel disease surveillance
Part of Digestive system clinical trials.
This trial looks at whether taking random biopsies during a routine colonoscopy is helpful for people with inflammatory bowel disease (IBD) who are at risk for colon cancer. It aims to understand if random biopsies can detect early signs of cancer or pre-cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have ulcerative colitis, IBD of the colon type, or Crohn's disease affecting at least one-third of your colon.
- Your IBD has been present for at least 8 years (or you have other risk factors like primary sclerosing cholangitis, a history of abnormal cell growth, or a family history of colon cancer).
- You are scheduled for a routine colonoscopy specifically to check for dysplasia (abnormal cells that might lead to cancer).
- You have never had colorectal cancer, and any past abnormal growths (like dysplasia or sessile serrated adenomas) have been fully removed.
- You have not had a colonoscopy for dysplasia surveillance in the last 11 months (unless that colonoscopy was incomplete or found no problems).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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