Study of why some bowel inflammation treatments don’t work
Part of Digestive system clinical trials.
This study looks at blood and/or tissue “molecular” (cell-level) reasons why treatments don’t fully work in adults with Crohn’s disease or ulcerative colitis. If you are starting a biologic or small-molecule medicine and still have moderate to severe symptoms, you may be able to contribute to research that helps improve future care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be an adult (18 or older) and have signed the consent form
- Have Crohn’s disease or ulcerative colitis for at least 3 months
- Have moderate to severe disease based on specific scoring tests (Mayo score for ulcerative colitis or CDAI for Crohn’s)
- Be starting a new treatment like an anti-TNF, anti-IL 21/23, anti-integrin, or a JAK inhibitor
- Have a colonoscopy planned as part of routine care to check how active the disease is
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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