Comparing PET and MRI scans before prostate cancer surgery
Part of Cancer, Kidney & urinary clinical trials.
This trial tests if a special PET scan (PSMA-PET) plus MRI is better than MRI alone at finding the full extent of high-risk prostate cancer before surgery. It aims to improve surgical planning by checking scan results against the removed prostate tissue.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with prostate cancer and are scheduled for surgery to remove your prostate.
- You already had a PSMA-PET scan as part of your regular care.
- At least 4 weeks have passed since your last prostate biopsy.
- Your cancer is considered high-risk, meaning it has a high Gleason score (8 or above), is likely growing outside the prostate (stage T3), or your PSA is 20-49.
- You are 18 or older and can provide written consent.
- You do not have metal implants or other reasons that prevent an MRI or PET scan (like claustrophobia or severe back pain).
- You have not had hormone therapy (anti-testosterone treatment) for your prostate cancer.
- You have not had a TUR-P procedure in the last 6 months.
- Your cancer has not spread to bones, organs, or lymph nodes outside the pelvis.
- You have no other recent cancer (except skin cancer) and your kidneys work well (creatinine clearance normal).
- You do not have tinnitus or significant hearing loss.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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