Sodium bicarbonate quadruple therapy for H. pylori infection
Part of Digestive system, Infections clinical trials.
This trial tests if adding sodium bicarbonate to standard quadruple therapy works better for clearing H. pylori stomach infections. It is for adults who have not been treated for H. pylori before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have never taken treatment to get rid of H. pylori before.
- You have tested positive for H. pylori (through a biopsy, breath test, or stool test).
- If you are over 40 years old, have warning symptoms, or have a family history of stomach cancer, you must have had a stomach scope (endoscopy) before starting treatment.
- You have not taken antibiotics or bismuth in the last 4 weeks, or acid-reducing drugs in the last 2 weeks.
- You do not have a serious stomach ulcer with bleeding, a past esophagus or stomach surgery, or a known allergy to the study drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a combination of four medications to treat H. pylori, a bacteria that can cause stomach ulcers and other issues. The goal is to see if this newer therapy works well for people who are infected.
This trial tests whether adding bismuth to standard treatment works better for children with stomach ulcers caused by H. pylori infection. If your child has been diagnosed with an H. pylori ulcer, this study could help find the best medicine.
This trial compares two treatments for H. pylori infection: a high-dose two-drug regimen and a four-drug regimen containing minocycline. It aims to find which is more effective and better tolerated.
This study tests how long (10 or 14 days) a combination of four medicines (bismuth quadruple therapy) should be taken to best treat H. pylori infection, and whether the best duration differs between women and men. It aims to find the shortest effective treatment to reduce side effects.
This trial tests if a newer acid-blocking medicine works better than a standard one when given with antibiotics and bismuth for treating H. pylori infection, a bacteria that can cause stomach ulcers. It is for adults who have not had treatment for H. pylori before.
This study tests a combination of a probiotic (Saccharomyces boulardii) plus a standard bismuth-based four-drug treatment for people whose H. pylori infection has not been cured by previous treatments. It aims to see if adding the probiotic helps the treatment work better and cause fewer side effects.
Hear when a new Helicobacter Pylori Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.