Comparing two acid-blocking drugs for H. pylori treatment
Part of Digestive system, Infections clinical trials.
This trial tests if a newer acid-blocking medicine works better than a standard one when given with antibiotics and bismuth for treating H. pylori infection, a bacteria that can cause stomach ulcers. It is for adults who have not had treatment for H. pylori before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- 18 years old or older
- Confirmed H. pylori infection from a stool or breath test
- No prior treatment for H. pylori
- No antibiotics, acid reducers (PPI), or bismuth in the last 4 weeks
- No major organ failure, pregnancy, or known drug allergies
- No stomach surgery in the past
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests two different ways to treat Helicobacter pylori (H. pylori), a bacteria that can cause stomach ulcers. One treatment combines three medicines (bismuth, amoxicillin, and vonoprazan), and the other uses four medicines (bismuth quadruple therapy). The goal is to see which works better.
This trial tests two different antibiotic combinations (both including bismuth) to see which works better at getting rid of an H. pylori infection in the stomach. The goal is to find a more effective way to clear the infection and reduce stomach problems.
This trial compares two different antibiotic combinations to treat H. pylori, a common stomach bacteria that causes indigestion and ulcers. One uses a newer acid-blocking medicine (vonoprazan) and the other uses a standard one (esomeprazole), both paired with antibiotics.
This trial tests a combination of four medications to treat H. pylori, a bacteria that can cause stomach ulcers and other issues. The goal is to see if this newer therapy works well for people who are infected.
This trial compares two treatments for H. pylori infection: a high-dose two-drug regimen and a four-drug regimen containing minocycline. It aims to find which is more effective and better tolerated.
This trial tests if adding sodium bicarbonate to standard quadruple therapy works better for clearing H. pylori stomach infections. It is for adults who have not been treated for H. pylori before.
Hear when a new Treatment trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.