Clin2
NCT07139366Likely a fitRecruiting

Probiotic plus bismuth combo for stubborn H. pylori

GastritisDyspepsiaHelicobacter Pylori InfectionGastric CancerPeptic Ulcer

Treatments studied

Part of Cancer, Digestive system clinical trials.

This study tests a combination of a probiotic (Saccharomyces boulardii) plus a standard bismuth-based four-drug treatment for people whose H. pylori infection has not been cured by previous treatments. It aims to see if adding the probiotic helps the treatment work better and cause fewer side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
1,248 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have already tried treatment for H. pylori infection that didn't work.
  • If you are a woman who could become pregnant, you agree to use birth control during the study and for 30 days after.
  • You have not taken antibiotics tetracycline or furazolidone before for H. pylori.
  • You do not have serious health issues like heart, lung, or kidney disease, or a history of cancer.
  • You have not used certain medications recently (like proton pump inhibitors, antibiotics, or bismuth) before the study begins.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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