Spine arthritis in IBD patients on TNF inhibitors
Part of Bones, joints & muscles, Digestive system clinical trials.
This study looks at how often people with inflammatory bowel disease (IBD) who take TNF inhibitor drugs develop a type of arthritis in the spine (axial spondyloarthritis). It also checks how well the TNF inhibitors control the arthritis symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have inflammatory bowel disease (ulcerative colitis or Crohn's disease).
- You are currently taking or have taken a TNF inhibitor medication (like infliximab or adalimumab).
- You have low back pain for at least 3 months that improves with exercise and not with rest.
- You have limited movement in your lower back or chest expansion as measured by your doctor.
- You have X-ray evidence of sacroiliitis (inflammation of the sacroiliac joints).
- You do not have other autoimmune diseases, diabetes, chronic liver or kidney failure, cancer, or other back problems like fractures or tumors.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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