Testing a malaria infection in healthy adults
Part of Infections clinical trials.
This study gives healthy adults who have never had malaria a controlled infection with the parasite that causes malaria, to see if it is safe and if mosquitoes can pick up the parasite from them. It may help develop new ways to prevent malaria.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 54 years old.
- Your red blood cells must have a specific protein called Duffy antigen (a blood test will check this).
- You must pass a short test about malaria to show you understand the study.
- You must have reliable access to the hospital for the whole study.
- If you could become pregnant, you must use reliable birth control from 28 days before the study until the end.
- You must not live alone from when you get the infection until you complete malaria treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study screens healthy adults to see who can join future malaria vaccine or investigational malaria drug studies, including a controlled malaria exposure. It may help researchers test safer vaccines/drugs, but participation requires good health and strict medical eligibility.
This study uses PET/CT scans to look at how a controlled malaria infection affects different organs in the body. It is for healthy adults already taking part in a malaria vaccine or infection study at NIH.
This study tests two different malaria vaccines to see which is safer and works better. Participants will receive one of the vaccines and then be exposed to a safe form of the malaria parasite to check if it protects them.
This study tests a new long-acting injection to prevent malaria. It checks safety and how the body handles the drug in healthy adults and adolescents in Rwanda.
This study tests an experimental malaria vaccine in healthy adults. The vaccine is given along with other medicines and a controlled exposure to mosquito bites to see how well it protects against malaria.
This study will expose healthy adults to a small number of mosquito bites carrying the P. vivax malaria parasite to learn how many bites are needed to cause infection. Participants will be closely monitored and treated in the hospital to ensure safety.
Hear when a new Malaria trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.