Clinical trials
Malaria clinical trials
Below are recruiting malaria clinical trials, each written for real people, not researchers. We’re tracking 55 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06529237Recruiting
Malaria study for children and pregnant women in Mozambique
This study looks at how malaria spreads in Mozambique by testing children and pregnant women with fever. If you or your child may have malaria, participating could help researchers understand and fight the disease better.
Manhiça, Maputo ProvinceAges 6 months+ - NCT07389057Recruiting
Malaria prevention study with combined medicines in Ghana
This trial tests if giving two malaria medicines together (dihydroartemisinin piperaquine and primaquine) to everyone in a community can help reduce malaria. It is for people living in high-risk areas in eastern Ghana.
Accra, Eastern RegionAges 3 months+ - NCT05071079Recruiting
Study infects volunteers with a malaria germ to test treatment
This study gives healthy volunteers a controlled infection with a type of malaria (vivax) to see how the infection behaves and how well curative anti-malaria medicine works. It may help researchers better design and test future malaria vaccines and treatments.
BangkokAges 20–55 - NCT07749911Recruiting
Vaccine effectiveness study for malaria in young children
This study looks at how well the R21/Matrix-M malaria vaccine works in real-life settings for children under 5. If your child is eligible for the vaccine and has a fever, they may be able to join and help us understand the vaccine's impact.
Boromo, Boucle MouhounAges 5 months–5 years - NCT07416461Recruiting
Malaria vaccine study for reducing Salmonella risk
This study looks at whether malaria vaccines can also help lower the risk of a serious bacterial infection called invasive non-typhoidal Salmonella (iNTS). If you have a fever, you may be able to join and help researchers understand this connection.
KinshasaAges Any age - NCT05788094RecruitingPhase 4
Compare two medicines for P. vivax malaria
This study tests how well a malaria treatment plan works for people with P. vivax malaria who don’t have another malaria type at the same time. It aims to see whether adding or using different medicines (ACT vs chloroquine with tafenoquine) helps clear infection and prevent return of disease.
Mae Sot, Changwat TakAges 18 years+ - NCT07009847Recruiting
Study of the R21/Matrix-M malaria vaccine
This study looks at how well the R21/Matrix-M malaria vaccine works and how safe it is in children who received it. It compares children who got malaria (or died) to healthy children who also got the vaccine.
Bousse, Burkina FasoAges 5 months+ - NCT07038837RecruitingPhase 4
Comparing two ways to give the R21 malaria vaccine in Chad
This study tests two ways of giving the R21 malaria vaccine to children in Chad during the rainy season. One way follows the routine vaccination schedule, and the other gives the vaccine at the same time as seasonal malaria prevention medication.
Moïssala, Mandoul RegionAges 6 months–4.9 years - NCT06962319RecruitingPhase 3
Malaria treatment safety in early pregnancy
This trial tests how safe antimalarial drugs are during the first few months of pregnancy. It aims to find treatments that protect both mother and baby.
NanoroAges 16 years+ - NCT06958198RecruitingPhase 1
Testing a new multi-stage malaria vaccine in adults and children
This trial tests a new combination of experimental malaria vaccines to see if they are safe and help protect against malaria. It includes both adults and young children in malaria-affected areas.
Siglé, Boulkiemdé ProvinceAges 5 months–35 years - NCT06923592RecruitingPhase 3
Blood test and treatment for vivax malaria in Ethiopia and Madagascar
This trial tests whether using a blood test to find and treat people infected with a type of malaria called Plasmodium vivax can reduce the spread of the disease. It may help you and your community stay healthier.
Addis AbabaAges 1 year+ - NCT06860178RecruitingPhase 4
Malaria vaccine plus seasonal prevention for children
This trial tests if adding a malaria vaccine to seasonal preventive medicines helps protect young children better from malaria. It is for healthy children living in certain areas of Burkina Faso and Mali.
OuagadougouAges 3 months–4.9 years - NCT06806956Enrolling by invitation
Severe Malaria in Rural Children Study
This study looks at severe malaria in children from remote areas. It compares children with malaria, children with other severe fevers, and those with uncomplicated malaria to improve treatment in hard-to-reach villages.
Kinshasa, Kinshasa CityAges 6 months–5 years - NCT06607003RecruitingPhase 1
Testing a malaria infection in healthy adults
This study gives healthy adults who have never had malaria a controlled infection with the parasite that causes malaria, to see if it is safe and if mosquitoes can pick up the parasite from them. It may help develop new ways to prevent malaria.
Bethesda, MarylandAges 18–54 - NCT05690841RecruitingPhase 3
Medication campaign to eliminate malaria in nearby villages
This Phase 3 trial tests whether giving malaria medicine to people in high-risk households (a “mass drug administration” campaign) can stop local relapses and eliminate vivax malaria. If you live close to a recent malaria case, you may be offered a preventive dose, based on age and medical safety checks.
IquitosAges Any age - NCT02639299Recruiting
Screening healthy adults for malaria vaccines and drug studies
This study screens healthy adults to see who can join future malaria vaccine or investigational malaria drug studies, including a controlled malaria exposure. It may help researchers test safer vaccines/drugs, but participation requires good health and strict medical eligibility.
Bethesda, MarylandAges 18–50 - NCT02471378Recruiting
Testing a malaria vaccine in pregnant people with malaria
This study looks at lab tests for malaria vaccine candidates in pregnant women who currently have malaria. It may help researchers understand which vaccine approaches are safest and most promising for pregnancy.
BamakoAges 15–25 - NCT07811908RecruitingPhase 2
Testing a new malaria treatment for children
This study tests a new malaria treatment for children with mild (uncomplicated) malaria. The goal is to see if the treatment safely and effectively clears the infection.
BanforaAges 2–12 - NCT07770048Recruiting
Study of hidden malaria in Odisha, India
This study looks for malaria infections that do not cause symptoms, to better find and treat them and learn how mosquitoes spread the disease. It may help improve testing and prevention in your community.
Bhubaneswar, OdishaAges 1–69 - NCT07758985RecruitingPhase 1
Testing a pill's safety and effect on mosquitoes in healthy adults
This study tests a new pill called lotilaner for safety and how well it works to kill mosquitoes that carry malaria. It is for healthy adults in Mali and may help future malaria prevention efforts.
BamakoAges 18–55 - NCT06555809Recruiting
Artesunate study for infants with severe malaria
This trial studies how artesunate works in infants under 2 years old being treated for severe malaria. It aims to learn more about the medicine to help improve treatment for babies.
ParisAges 1 minute–1.9 years - NCT07559370RecruitingPhase 2
Imatinib Plus Artemether-Lumefantrine for Uncomplicated Malaria
This trial tests whether adding a cancer drug called imatinib to standard malaria treatment works better and is safe. Researchers will enroll adults and children with uncomplicated malaria caused by P. falciparum parasites and monitor them in the hospital for 2–3 days.
KisumuAges 1–55 - NCT07468513RecruitingPhase 4
Primaquine for vivax malaria in G6PD-intermediate or deficient adults
This trial tests how well the drug primaquine works for people with vivax malaria who have intermediate or low levels of an enzyme called G6PD. It aims to find safe and effective treatment options for this group.
ManausAges 18 years+ - NCT07456969Recruiting
Breath test for malaria diagnosis in Ethiopia
This trial is testing a new, non-invasive way to diagnose malaria by collecting and analyzing your breath. If you have a fever and are at least 12 years old, you may be able to help researchers see if this breath test works well.
Gonder, AmharaAges 12 years+
Hear when a new Malaria trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Malaria trials by city
Studies with a site in or near these metro areas.
Malaria trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for malaria?
- Yes. Clin2 currently lists 55 recruiting malaria studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malaria trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malaria trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.