Three-drug combination for newly diagnosed AML in older adults
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This clinical trial tests a combination of three drugs: a liposomal form of mitoxantrone (a type of chemotherapy), cytarabine (another chemo drug), and venetoclax (a targeted therapy). The goal is to see if this combination is safe and works well for older adults (ages 60-70) who have just been diagnosed with AML and cannot have standard intensive chemotherapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 60 and 70 years old.
- You must have been recently diagnosed with acute myeloid leukemia (AML) – not a type called promyelocytic leukemia, and not AML that came from another blood disorder or past cancer treatment.
- You should be physically active enough to take care of yourself (ECOG score 0-2).
- Your liver and kidneys must work well enough (based on blood tests).
- You must not have serious heart problems or a history of certain heart conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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