Chidamide plus AK112 for advanced sarcoma after first treatment
Part of Cancer clinical trials.
This trial tests two new drugs (chidamide and AK112) together for people with advanced bone or soft tissue sarcoma that has not responded to standard first-line treatment. The goal is to see if this combination can shrink tumors or slow their growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of bone or soft tissue sarcoma that has spread or come back after first-line treatment.
- You are between 18 and 75 years old and able to take care of yourself (ECOG 0-1).
- Your organs (bone marrow, liver, kidneys, heart, thyroid) are working well enough, based on blood tests and an ultrasound of your heart.
- You have not had certain other treatments before, including a drug like chidamide or AK112 (a type of immunotherapy).
- You are not pregnant or breastfeeding, and you agree to use birth control during the study and for 6 months after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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