Comparing rescue treatments for severe ulcerative colitis flare
Part of Digestive system clinical trials.
This trial tests two different medicines, infliximab and upadacitinib, to see which works better for people with severe ulcerative colitis that hasn't improved after 3 days of IV steroids. The goal is to find the best rescue option to help you feel better and avoid surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 64 years old
- You have a confirmed diagnosis of ulcerative colitis
- You are currently in the hospital with a severe flare that did not get better after 3 days of IV steroids
- You have had a colonoscopy or flexible sigmoidoscopy in the last 4 weeks showing active inflammation (score of 2 or higher)
- You have not taken infliximab or a JAK inhibitor (like upadacitinib) before for your UC
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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