Endometrial cytology and methylation testing for endometrial cancer screening
Part of Cancer, Women’s health & pregnancy clinical trials.
This study tests two less invasive methods—sampling cells from the lining of the uterus (endometrial cytology) and checking DNA changes in the cervix—to see if they can help detect endometrial cancer or atypical hyperplasia, and to monitor response in people who are preserving their fertility. It aims to find a gentler alternative to traditional biopsy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are postmenopausal and have a thickened uterine lining (over 5 mm) or a mass inside the uterus seen on ultrasound
- You are currently receiving fertility-sparing treatment for endometrial cancer or atypical hyperplasia and need follow-up
- You have a thickened uterine lining after taking hormone therapy for breast cancer
- You are willing to sign an informed consent form and attend follow-up visits
- You do not have cervical cancer, severe health issues preventing the procedure, or an active infection
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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