Nasal provocation test for irritant rhinitis diagnosis
Part of Ear, nose & throat clinical trials.
This study is testing a new nasal spray challenge, called the CDA nasal provocation test, to help doctors safely and accurately diagnose a condition called irritable rhinitis (IR). If you have long-term nasal symptoms but no allergies, this test could help confirm the cause and guide better treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old.
- You must have had rhinitis symptoms (like a runny or stuffy nose) for more than 2 years, often triggered by things like smoke, perfumes, or temperature changes.
- You must have tested negative for common allergies (allergen-specific IgE tests).
- You must not have used certain medications (like antihistamines, steroids, or immune drugs) in the past month.
- You must be a non-smoker.
- You must not be pregnant or breastfeeding, and you must not have had nasal surgery in the last 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study uses a nasal allergen provocation test to help diagnose chronic rhinitis more accurately. If you have allergic rhinitis or are a healthy volunteer, you may help researchers learn how well this test works.
This study looks at the fluids from your nose to find unique markers that might help diagnose chronic rhinitis more accurately. By studying your nasal secretions, researchers hope to understand the condition better and develop better tests.
This study looks at chronic rhinitis (long-term stuffy or runny nose) in Chinese adults. It aims to understand how common it is and what causes it.
This trial compares two methods of a procedure that targets nasal nerves to reduce chronic rhinitis symptoms. It may help people whose rhinitis is not caused by allergies.
This study uses a nasal allergen “provocation” test to help decide how to start and monitor allergy immunotherapy (allergy shots or drops). It may help doctors better track whether the treatment is working for people with allergic rhinitis.
This study compares two combination treatments for moderate to severe allergic rhinitis (hay fever). One group uses a corticosteroid nasal spray plus an antihistamine nasal spray, and the other uses the same spray plus an oral antihistamine pill. The goal is to see which combination better improves symptoms like sneezing, runny nose, and congestion.
Hear when a new Chronic Rhinitis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.