Clin2
NCT06694454Possibly a fitSuspended

Inhaled azacytidine plus chemo and durvalumab before lung cancer surgery

Non-small Cell Lung Cancer (NSCLC)Carcinoma, Non-Small Cell LungNon-Small Cell Lung CarcinomaNon Small Cell Lung CancerNon Small Cell Lung Carcinoma

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests adding an inhaled drug (azacytidine) to standard chemotherapy and durvalumab before surgery for early-stage lung cancer. The goal is to see if this combination can shrink tumors and improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
60 people
Ages
18 years to 120 years
Study type
Interventional

Who can take part

  • You must have stage IB, II, or IIIA non-small cell lung cancer that can be removed by surgery.
  • You must be willing to have a biopsy before treatment and have the tumor safely accessible for a biopsy.
  • You have not had any prior treatment for this lung cancer.
  • You are at least 18 years old and weigh more than 66 pounds (30 kg).
  • You must be in good enough health to handle surgery, with adequate lung function.
  • If you can become pregnant or father a child, you must agree to use effective birth control during and after treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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