Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,345 recruiting studies in this area right now.
By phase
- Not applicable4,049
- Phase 2834
- Phase 1455
- Phase 3423
- Phase 1/Phase 2308
- Phase 4211
- Phase 2/Phase 365
Top conditions
- Lung Cancer416
- Asthma193
- Non-Small Cell Lung Cancer183
- Non Small Cell Lung Cancer176
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea143
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1993
- Colorectal Cancer88
- Chronic Obstructive Pulmonary Disease86
- NSCLC86
- Cystic Fibrosis76
- Chronic Obstructive Pulmonary Disease (COPD)75
- Interstitial Lung Disease75
- Ovarian Cancer70
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca66
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development39
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California382
- Alabama177
- Arizona154
- Massachusetts120
- Florida119
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois72
Recruiting studies6,345 total
- NCT07159763RecruitingPhase 3
Study of a new medicine to prevent flu
This study tests a new type of flu prevention medicine (called a monoclonal antibody) given as an injection. It is for people at higher risk of getting the flu, including those with certain health conditions or weakened immune systems.
Anniston, AlabamaAges 12 years+ - NCT07760012Recruiting
Pet scan with new tracer for solid tumors
This study uses a new imaging tracer, called 68Ga-SorB, during a PET/CT scan to look at tumors. It may help doctors see cancer more clearly. The trial is for adults with certain types of solid tumors (such as melanoma, liver, lung, breast, pancreatic, ovarian, or bile duct cancer) who need a PET/CT scan as part of their care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04573062Recruiting
Long COVID recovery study at the NIH
This study looks at how people recover from COVID-19 over time, including those with ongoing symptoms (Long COVID). It involves phone interviews and possibly in-person evaluations to understand long-term effects.
Bethesda, MarylandAges 18–100 - NCT07875036Recruiting
Breathing exercises for COPD-related shortness of breath
This study compares two types of breathing exercises to see which one works better for reducing shortness of breath and improving lung function in people with mild to moderate COPD.
RawalpindiAges 40–75 - NCT05780450Recruiting
Brain stimulation for long covid headaches and pain
This trial tests a safe, non-invasive brain stimulation technique (transcranial direct current stimulation, or tDCS) to see if it can reduce persistent headaches and chronic pain in people with long covid. If you have ongoing pain after a confirmed covid infection, this could offer a new way to find relief.
Paiporta, ValenciaAges 16 years+ - NCT07874490RecruitingPhase 2
Osimertinib plus cyclosporine for advanced lung cancer
This study tests whether adding cyclosporine to the standard drug osimertinib can make it work better in people with advanced non-small cell lung cancer that has a specific EGFR gene change. You can join even if you haven't started treatment or have just started osimertinib within the last 3 weeks.
New York, New YorkAges 18 years+ - NCT07458347RecruitingPhase 1
Study of a new drug for advanced solid tumors with a KRAS mutation
This trial tests a new pill, KST-6051, for people with advanced solid tumors (like lung, pancreatic, or colorectal cancer) that have a specific genetic change called a KRAS mutation. The goal is to see if the drug can shrink or control the cancer, and to find the best dose.
Los Angeles, CaliforniaAges 18 years+ - NCT07020221RecruitingPhase 1/Phase 2
Study of VS-7375 for cancers with a KRAS G12D mutation
This study tests an experimental drug called VS-7375 for people with advanced solid tumors that have a specific genetic change called KRAS G12D. The goal is to see if the drug can shrink tumors or slow their growth.
Los Angeles, CaliforniaAges 18 years+ - NCT07875049Recruiting
Breathing exercises for COPD patients after heart bypass surgery
This trial tests whether adding a device called a Flutter to standard chest physical therapy can improve your breathing and lung function after heart bypass surgery. It may help you recover better if you have mild to moderate COPD.
RawalpindiAges 40–70 - NCT05798923RecruitingPhase 2
Study of a new drug for pulmonary hypertension with lung disease
This trial tests an investigational drug called LAM-001 for people who have pulmonary hypertension (high blood pressure in the lungs) along with a type of lung disease called interstitial lung disease. The drug may help improve symptoms and daily function. This study will see if the drug is safe and helpful for this condition.
Tucson, ArizonaAges 18–85 - NCT07874581Recruiting
Study of MRG003 for small cell lung cancer that has returned
This study tests a new drug, MRG003, for people with a type of lung cancer called small cell lung cancer that has spread or come back after earlier treatment. The goal is to see if this drug can help shrink tumors or slow the cancer's growth.
ShanghaiAges 18 years+ - NCT07521319Recruiting
Wearable device guide for sleep apnea and insomnia
This study tests a wearable device that helps guide treatment for people who have both sleep apnea and insomnia. It may help improve your sleep quality and daytime symptoms.
Tainan, TaiwanAges 20–80 - NCT06570473RecruitingPhase 2
RV failure treatment trial for pulmonary hypertension patients
This trial is testing two heart medications, empagliflozin and ranolazine, to see if they can improve right heart function in people with pulmonary hypertension and right ventricular failure. Participants will monitor their symptoms using a smartphone or tablet.
Calgary, AlbertaAges 18 years+ - NCT07463885Recruiting
Breathing on your own vs machine breathing for low oxygen
This study tests whether letting patients with serious breathing problems breathe on their own (with a breathing tube still in place) is better than the usual way of using the ventilator to do all the breathing. It may lead to faster recovery and less harm.
Oslo, OsloAges 18 years+ - NCT07667400RecruitingPhase 1/Phase 2
Docetaxel plus SX-682 for advanced head and neck or prostate cancer
This trial studies a combination of the chemotherapy drug docetaxel and an investigational drug called SX-682 for people with certain advanced head and neck cancers or prostate cancer. The goal is to see if the combination is safe and effective.
Bethesda, MarylandAges 18–120 - NCT06366724RecruitingPhase 2
Life Improvement Trial for ME/CFS
This trial tests a new treatment for ME/CFS (chronic fatigue syndrome) that includes symptoms like dizziness when standing. It uses a smartphone app to track your progress and aims to see if the treatment can improve your daily life.
Boston, MassachusettsAges 18–70 - NCT07701096Enrolling by invitation
Home breathing support monitoring for advanced COPD
This study tests a home monitoring system that watches how well noninvasive breathing support (a mask that helps you breathe) works for people with severe COPD. The system sends early warnings to your care team if your breathing patterns change, which may help prevent flare-ups.
BeijingAges 18 years+ - NCT05636969Recruiting
Pre-surgery exercise program for lung cancer treatment
This trial looks at whether a “prehabilitation” (guided exercise and fitness preparation) program helps people with non-small cell lung cancer get ready for surgery after starting treatment before surgery. It may help you tolerate treatment and surgery better if you can do the required fitness testing and procedures.
Barcelona, BarcelonaAges 18 years+ - NCT06776783RecruitingPhase 3
Testing a new surfactant for breathing problems in premature babies
This study tests a new medicine called APC-0101, a type of surfactant, for premature babies with breathing problems (respiratory distress syndrome). It may help their lungs work better and reduce the need for more breathing support.
Little Rock, ArkansasAges 1 hour–1 day - NCT07612878Recruiting
Registry tracking COPD patients starting dupilumab treatment
This is a registry—an observational study tracking patients with COPD (chronic lung disease) who are newly starting a medication called dupilumab. Researchers will follow your health outcomes to learn how well this treatment works in real-world practice.
Indianapolis, IndianaAges 40 years+ - NCT07253883Recruiting
New breathing device test for asthma and COPD
This trial is testing a new breathing device that may be as accurate as standard tests for diagnosing asthma and COPD. It could offer a simpler and quicker way to check your lung health.
Liverpool, MerseysideAges 18–110 - NCT07867184Enrolling by invitation
Firefighter lung health study
This study looks at how firefighting affects your lungs over time. By tracking your health and exposures, researchers hope to find ways to prevent lung problems in firefighters.
Bethesda, MarylandAges 18–65 - NCT06239194RecruitingPhase 1/Phase 2
MdX2001 for advanced solid tumors
This trial tests a new drug, MDX2001, for people with advanced solid tumors that have spread. The study aims to find the best dose and see how well it works.
Denver, ColoradoAges 18 years+ - NCT07861542RecruitingPhase 4
COVID-19 booster vaccine for older adults and high-risk people
This trial tests an updated COVID-19 booster vaccine designed to improve protection for people who are older or have health conditions that increase their risk of severe COVID-19. If you qualify, you would receive one dose of the study vaccine and be monitored for safety and immune response.
Fair Oaks, CaliforniaAges 12 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,345 recruiting pulmonology studies from the U.S. registry right now, out of 9,869 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.