Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,622 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2849
- Phase 1471
- Phase 3423
- Phase 1/Phase 2311
- Phase 4207
- Phase 2/Phase 368
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD144
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome73
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Chinese University of Hong Kong35
- Riphah International University34
Where studies are running
- California389
- Alabama175
- Arizona154
- Massachusetts128
- Florida119
- New York113
- Maryland111
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,622 total
- NCT07613918Recruiting
Brain Blood Flow Monitoring in Critically Ill Children
This study measures how well blood flows to your child's brain while they're in the intensive care unit on a breathing machine. Understanding this flow may help doctors better care for critically ill children.
Madison, WisconsinAges 1 day–17 years - NCT06940219Recruiting
Comparing delayed vs. rapid intubation in emergencies
This trial tests whether delaying medication to start breathing support (by waiting 60 seconds after sedation) is safer for critically ill adults needing emergency intubation. Standard practice is to give sedation then immediately insert the tube.
Leipzig, SaxonyAges 18 years+ - NCT06884189Recruiting
Pesticide exposure study in apple orchard areas
This study looks at how people living or working around apple orchards are exposed to certain plant protection products (pesticides). By joining, you can help researchers understand potential health risks and improve safety guidelines.
BerlinAges 18 years+ - NCT06881576Recruiting
Video study of intubation in children having surgery
This trial is studying how doctors place breathing tubes (intubation) in children during planned surgeries. Researchers will use video to review and improve the process, which may help make future procedures safer.
Madrid, MadridAges birth–18 years - NCT06374030Recruiting
Airway management study in Dutch emergency departments
This study looks back at medical records of patients who had a breathing tube placed in Dutch emergency departments from 2019 to 2023. It aims to understand how doctors manage airways in emergency settings.
LeeuwardenAges Any age - NCT06303518Recruiting
Carbon dioxide and brain activity in children under anesthesia
This study looks at how levels of carbon dioxide in the breath affect brain activity during anesthesia in children. It helps doctors understand the best way to monitor and keep a child safely asleep during surgery.
Vancouver, British ColumbiaAges 3–11 - NCT05163925Recruiting
Study of a heart-lung device for emergency life support
This trial looks at using a specific heart-lung support machine (the EUROSETS ECMOLIFE system) for adults who need urgent “extra” circulation support. It may help clinicians understand how well the device works in serious situations like shock, cardiac arrest, or after heart surgery.
ViennaAges 18 years+ - NCT04865276Recruiting
Quit tobacco with a phone-based support program
This study tests a phone (mHealth) program designed to help people stop using tobacco. You may be assigned to either the program or a comparison group, based on your location and the study plan.
Londrina, ParanáAges 18 years+ - NCT06813365RecruitingPhase 1
A targeted therapy for EGFR-mutated advanced lung cancer
This trial is testing a new targeted pill for people with EGFR-positive non-small cell lung cancer. It's designed for those whose cancer has grown after other treatments, and it works by blocking a specific protein that helps the cancer grow.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07792746Recruiting
Sleep apnea markers and use of CPAP therapy
This study looks at whether certain markers in sleep apnea patients can predict how well they will stick with CPAP (a mask that helps you breathe at night). If you're newly diagnosed and about to start CPAP, this could help personalize your care.
MontpellierAges 18 years+ - NCT07793500RecruitingEarly Phase 1
Nebulized drug for lung metastases from solid tumors
This study tests a new drug given as a mist you breathe in, for people whose cancer has spread to the lungs. The goal is to see if it can shrink tumors or slow their growth.
BeijingAges 18–75 - NCT07314593Recruiting
Fish oil for preventing colds and respiratory infections
This trial tests whether taking fish oil with free fatty acids can help healthy adults avoid colds and other respiratory infections. If you are generally healthy and willing to take fish oil capsules daily, you may be able to join.
ReykjavikAges 18–80 - NCT07554339RecruitingPhase 3
Calderasib and Durvalumab for Advanced Lung Cancer After Chemotherapy
This trial tests a combination of two drugs—calderasib (a targeted therapy) and durvalumab (an immunotherapy)—for people with a specific type of advanced lung cancer that has a KRAS G12C mutation. The goal is to prevent the cancer from coming back after standard chemotherapy and radiation treatment.
Lincoln, NebraskaAges 18 years+ - NCT07365241RecruitingPhase 3
Study of ABBV-706 vs standard care for advanced small cell lung cancer
This trial tests a new drug called ABBV-706 against standard treatments (topotecan, lurbinectedin, or amrubicin) for people with small cell lung cancer that has come back or stopped responding to previous therapies. The goal is to see if ABBV-706 works better at controlling the cancer.
Birmingham, AlabamaAges 18 years+ - NCT06780137RecruitingPhase 1/Phase 2
Gocatamig plus ifinatamab deruxtecan for advanced small cell lung cancer
This study tests two new drugs (gocatamig and ifinatamab deruxtecan) for people whose small cell lung cancer has spread or come back after standard chemotherapy. It aims to see if the combination works better than current options.
Aurora, ColoradoAges 18 years+ - NCT07792044Enrolling by invitation
Pain relief after shoulder surgery
This study tests a numbing medicine injected near the shoulder to see if it gives better pain relief after arthroscopic shoulder surgery than the standard approach. It might help you recover with less pain and fewer side effects.
Jiaxing, ZhejiangAges 18 years+ - NCT05624450RecruitingPhase 3
Test drug tozorakimab for hospitalized viral lung infection needing oxygen
This Phase 3 study tests tozorakimab to see if it helps people hospitalized with a viral lung infection that is causing low oxygen levels. You might qualify if you still need supplemental oxygen when the study starts.
Birmingham, AlabamaAges 18 years+ - NCT06951217RecruitingPhase 2
Long-term safety study of an inhaled drug for lung scarring
This study continues treatment for people who already completed a previous study with an Avalyn inhaled antifibrotic drug. It aims to check the long-term safety of the medication for patients with certain types of lung scarring.
Birmingham, AlabamaAges 18 years+ - NCT07190248RecruitingPhase 3
Calderasib plus other treatments for advanced non-small cell lung cancer
This trial tests a new drug called calderasib (MK-1084) combined with other treatments for people with advanced non-small cell lung cancer that cannot be surgically removed. It aims to see if this combination works better than current options.
Birmingham, AlabamaAges 18 years+ - NCT07586202RecruitingPhase 2
Testing New Drug Combinations Before Lung Cancer Surgery
This trial tests whether giving new drugs (amivantamab plus either lazertinib or chemotherapy) before surgery helps people with a specific type of lung cancer that can be removed. The goal is to shrink tumors and improve surgery outcomes.
Duarte, CaliforniaAges 18 years+ - NCT06472310Recruiting
Study of severe asthma in Russia (CORSAR)
This study looks at the health records of people in Russia with severe, uncontrolled asthma to understand their symptoms and treatments better. It does not involve any new medicine or treatment.
AstrakhanAges 18 years+ - NCT06819592RecruitingPhase 3
Preventing early lung infections after severe brain injury
This study tests whether giving an antibiotic (ceftriaxone) early after a severe brain injury can prevent lung infections caused by the breathing machine (ventilator). It is for adults in the ICU who recently started on a ventilator due to a brain emergency.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT06373289Recruiting
Blood pressure in lung arteries and oxygen levels in preemies
This study tests whether changing oxygen targets in preterm infants with high blood pressure in the lungs (pulmonary hypertension) helps their heart and lungs work better. It may help doctors find the best oxygen levels for these babies.
Birmingham, AlabamaAges 1 month–5 months - NCT07192042Recruiting
Testing a device to check sleep breathing in schizophrenia
This trial uses a non-wearable device to assess sleep-disordered breathing in people with schizophrenia who are hospitalized. It aims to understand if this easy method can help monitor sleep issues.
New Taipei CityAges 20–70
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,622 recruiting pulmonology studies from the U.S. registry right now, out of 10,481 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.