Chemo plus targeted therapy for high-risk HER2+ early breast cancer
Part of Cancer clinical trials.
This trial tests whether combining chemotherapy with targeted therapy works better for women with high-risk, HER2 positive early breast cancer that hasn't spread to lymph nodes. If you've had surgery and your tumor fits certain high-risk features, you may be eligible to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have had surgery (radical resection) for breast cancer at Peking University People's Hospital.
- Your cancer must be invasive, with a tumor size of T2 (2–5 cm), no spread to lymph nodes (N0), and HER2 positive.
- Your cancer should also have a high-risk feature, such as grade 3 (G3, fast-growing) or being hormone receptor negative (ER/PR negative).
- You must have agreed to join the PKUPH breast disease cohort study (a research registry).
- You cannot have had chemotherapy or targeted therapy before surgery (neoadjuvant therapy).
- Your cancer must not have spread to other parts of the body (metastatic) or be in both breasts.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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