Stent treatment for narrowed bowel areas in inflammatory bowel disease
Part of Digestive system clinical trials.
This trial tests a new way to treat narrowed areas (strictures) in the bowel caused by inflammatory bowel disease. A soft metal tube called a stent is placed using a scope to open the narrowing and relieve symptoms, which may help avoid surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years of age or older.
- You have inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis.
- You have a single narrowed area (stricture) in your bowel that is less than 6 cm long and causes symptoms.
- The stricture must be reachable with a standard colonoscope (in the colon or last part of the small intestine).
- You do not have severe active inflammation or complications like a fistula, abscess, or complete blockage.
- You are able to give informed consent and are medically fit for endoscopic therapy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a method to keep a metal stent in place using a plastic stent for people with non-cancerous narrowing in the first part of the small intestine. It may help if you have symptoms like nausea or vomiting and other treatments have not worked.
This trial compares two ways to treat narrowed areas (strictures) in the gut caused by Crohn's disease: endoscopic strictureplasty versus balloon dilation. It aims to see which method works better for people whose strictures are manageable with a scope.
This study looks at inflammation just before a narrowed section of the bowel in people with Crohn’s disease, using planned endoscopic balloon dilation. It may help doctors better understand what drives narrowing and inflammation so treatment can be timed and chosen more effectively.
This trial tests a new approach that combines two procedures (stricturotomy and balloon dilation) against stricturotomy alone to treat short narrowed areas (strictures) caused by Crohn's disease. The goal is to see which method works better for keeping the bowel open longer.
This study compares two endoscopic treatments for a narrowed area (stricture) in the small intestine caused by Crohn's disease. One method uses a balloon to stretch the narrowing, and the other makes a small cut with a special scope. The goal is to see which approach helps better and more safely.
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