Clin2
NCT06739278Worth exploringNot yet recruiting

Ustekinumab alone for perianal fistulizing crohn's disease

Crohn Disease

Part of Digestive system clinical trials.

This study looks at how well ustekinumab works on its own for people with perianal fistulizing Crohn's disease, a type of Crohn's that causes painful tunnels near the anus. If you are already taking ustekinumab without other Crohn's medicines, this trial may help show if it can improve your fistulas.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
119 people
Ages
18 years to 65 years
Study type
Observational

Who can take part

  • You have perianal fistulizing Crohn's disease — a type of Crohn's that causes abnormal tunnels (fistulas) near the anus.
  • You are currently being treated with ustekinumab (a biologic drug that calms the immune system).
  • You are not taking ustekinumab together with steroids, immunosuppressants, other biologics, or small molecule drugs.
  • You do not have other autoimmune diseases like lupus, rheumatoid arthritis, or Graves' disease.
  • You do not have serious infections (such as active tuberculosis, Epstein-Barr virus, or cytomegalovirus) or cancer.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05387031Recruiting
Ustekinumab for painful Crohn’s bowel narrowing

This trial tests ustekinumab, a medicine that calms immune inflammation, to see if it can improve symptoms in people with Crohn’s disease that causes bowel narrowing. It may help if your Crohn’s symptoms come from strictures (narrowed areas) seen on scans or endoscopy.

Beijing, Beijing Municipality
NCT06520397Recruiting· Phase 4
Combination therapy vs. higher dose ustekinumab for Crohn's

This trial tests whether a combination of two drugs (upadacitinib and ustekinumab) works better than a higher dose of ustekinumab alone for people with active Crohn's disease that hasn't responded well to previous treatments.

Guangzhou, Guangdong
NCT07872449Not yet recruiting· Phase 4
Treating difficult anal fistulas with risankizumab

This trial tests a drug called risankizumab (Skyrizi) for people whose Crohn's disease has led to anal fistulas that haven't improved with other treatments. The goal is to see if risankizumab can help these fistulas heal and stop draining.

Nishinomiya
NCT04372108Recruiting
Long-term safety study for ustekinumab vs other biologics

This study follows adults with Crohn’s disease or ulcerative colitis to compare the long-term safety of ustekinumab against other biologic medicines. It may help show how safe these treatments are over time, using medical records.

Houston, Texas
NCT07310095Recruiting· Phase 4
Study of ustekinumab for Crohn's disease with loss of response

This study tests a new treatment for people with Crohn's disease who have lost response to ustekinumab (Stelara). It aims to see if a different dosing or additional treatment can help regain control of symptoms.

Guangzhou
NCT05725876Recruiting· Phase 1
Imaging ustekinumab medicine movement in Crohn’s and psoriasis

This Phase 1 study uses a special camera to track how ustekinumab (a common biologic medicine) spreads in inflamed tissue. It aims to help researchers understand where the drug goes in Crohn’s disease and psoriasis, especially when standard treatments haven’t worked.

Groningen

Hear when a new Crohn Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.