Changkang Granules for Diarrhea-Predominant IBS
Part of Digestive system clinical trials.
This trial tests if Changkang Granules can reduce abdominal pain and diarrhea in people with irritable bowel syndrome (IBS) where the main symptom is loose stools. It is specifically for those whose condition fits a pattern in traditional Chinese medicine called 'Liver qi affecting the Spleen.'
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with IBS with diarrhea (based on the Rome IV criteria).
- You have had abdominal pain averaging at least a 3 on a 0-10 scale each week, and at least 2 days per week with very loose or watery stools (type 6 or 7 on the Bristol Stool Chart) during the run-in period.
- You have had a colonoscopy within the last year that shows no serious issues, or only minor findings like small polyps (≤5mm and no more than 3) that your doctor says are okay.
- You do not have major depression or anxiety (scores on standard questionnaires must be below certain cutoffs), and you have not taken certain medications for IBS, pain, or mental health in the last 4 weeks.
- You are not pregnant, breastfeeding, or planning to become pregnant during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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