Chinese herbal capsules for diarrhea-type irritable bowel syndrome
Part of Genetic & congenital, Skin clinical trials.
This study tests a traditional Chinese medicine capsule called Changji'an to see if it safely reduces diarrhea, pain, and bloating in people with diarrhea-type irritable bowel syndrome. These symptoms are thought to be caused by 'liver Qi invading the spleen.'
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with diarrhea-predominant irritable bowel syndrome (IBS-D), and a doctor has confirmed it fits the 'liver Qi invading spleen' pattern in traditional Chinese medicine.
- In the week before starting, you must have at least moderate abdominal pain, bloating, or discomfort (scored 3 or higher on a 0–10 scale), plus at least 2 days with loose or watery stools.
- A colonoscopy within the last year must show no serious problems — small polyps (5mm or smaller, up to 3) or minor issues like hemorrhoids are okay.
- You do not have severe anxiety or depression (mild is acceptable).
- You must stop certain IBS medicines, antidiarrheals, antidepressants, and other gut-related drugs at least 2 weeks before the trial starts.
- You are not pregnant, breastfeeding, or planning to conceive during the trial, and you agree to use effective birth control if needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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