Comparing two drugs to prevent heavy bleeding after childbirth
Treatments studied
Part of Women’s health & pregnancy clinical trials.
This trial compares two medications, carbetocin and misoprostol, to see which works better at preventing heavy bleeding (postpartum hemorrhage) after a vaginal delivery. It is for women who have one or more risk factors for heavy bleeding.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are pregnant with one baby (not twins or more)
- Your baby is positioned head down and your pregnancy is between 37 and 42 weeks
- You are planning a vaginal delivery (not a C-section)
- You have at least one risk factor for heavy bleeding after birth, such as having had 5 or more previous deliveries, a past heavy bleed, a past manual removal of the placenta, a baby estimated to weigh 4 kg or more, too much amniotic fluid, an infection of the membranes, or prolonged use of oxytocin during labor
- You are able to receive a medication to help the uterus contract after delivery and you give written consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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