Sugar digestion study for genetic condition and healthy volunteers
Part of Digestive system, Genetic & congenital clinical trials.
This study looks at how the body digests sugar, specifically sucrose, in people with a genetic condition called CSID (sucrase-isomaltase deficiency) and in healthy volunteers. By comparing the two groups, researchers hope to learn more about food sensitivities and digestive symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- For the CSID group: you must have a genetic test confirming you have CSID (congenital sucrase-isomaltase deficiency).
- For the healthy group: you must not have any digestive disorders, and you must not have the genetic variants that cause CSID (or have only certain variants, as specified).
- You must be able to complete a sucrose (sugar) challenge, which involves eating or drinking sugar to see how your body reacts.
- You cannot have any other major digestive diseases, diabetes, or uncontrolled thyroid problems (for CSID group).
- You cannot have had any bowel surgery (except appendix or gallbladder removal).
- You must be able to have an MRI scan (no metal implants, pacemaker, or severe claustrophobia).
- You cannot have taken part in another research study that tests an intervention in the last 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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