Cannabidiol oral solution for joint pain from hormone therapy in early breast cancer
Part of Cancer, Skin clinical trials.
This trial tests an oral solution of cannabidiol (CBD), a non-psychoactive cannabis compound, to see if it can ease joint pain caused by aromatase inhibitor therapy for early breast cancer. If it works, it could offer a new way to manage this common side effect.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and have been diagnosed with early-stage (I, II, or III) hormone-positive breast cancer.
- You have been taking an aromatase inhibitor (such as anastrozole, exemestane, or letrozole) for at least 3 weeks but no longer than 3 years.
- You are experiencing joint pain rated 4 or higher on a 0-10 scale, where 0 is no pain and 10 is the worst pain imaginable.
- You have not used opioids (strong painkillers like morphine), NSAIDs (like ibuprofen), or steroid medications for joint pain in the past 28 days.
- Your liver, kidney, and heart function are within acceptable ranges as determined by blood tests and an ECG.
- You are willing to use highly effective contraception (if of childbearing potential) and avoid becoming pregnant or fathering a child during the trial and for 3 months after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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