Perioperative chemo for resectable pancreatic cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a combination of chemotherapy drugs (liposomal irinotecan with fluorouracil, leucovorin, and oxaliplatin) given before and after surgery for pancreatic cancer that can be fully removed. It aims to see if this approach improves outcomes for patients with stage I or II disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with pancreatic cancer that has not spread beyond the pancreas and is surgically removable.
- You are between 20 and 75 years old.
- You have not received any prior treatment for your pancreatic cancer.
- Your overall health is good (able to perform daily activities without help).
- You have not had a heart attack, stroke, or serious heart problems in the last 6 months.
- You agree to use effective birth control if applicable, and you are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests 6 cycles of a chemotherapy combination called modified FOLFIRINOX before surgery for pancreatic cancer that can potentially be removed. The goal is to see if this approach improves outcomes for patients who might be candidates for another study called PANACHE02.
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This trial tests adding a new immunotherapy drug (addebelizumab) to standard chemotherapy for people with pancreatic cancer that can be removed by surgery. The goal is to see if the combination shrinks tumors more effectively before surgery.
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This Phase 2 trial tests a chemotherapy plan given before surgery (called “neoadjuvant” treatment) for people with pancreatic adenocarcinoma that looks resectable or borderline resectable on scans. The goal is to see how well this adaptive chemotherapy approach works and whether it can improve outcomes before an operation.
This trial tests a combination of chemotherapy drugs (irinotecan liposome, 5-FU, leucovorin, and oxaliplatin) given before and after surgery for people with pancreatic cancer that is on the border of being removable. The goal is to see if this treatment helps shrink the tumor and improve outcomes.
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