Comparing two blood-transfusion strategies for liver patients before procedures
Part of Digestive system clinical trials.
This trial tests whether using a slightly different target on a blood-clotting test (ROTEM) can reduce the need for blood transfusions in people with liver disease who need a procedure. If you have cirrhosis or ACLF with severe clotting problems, this study may help your doctors decide how much blood product to give you before the procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have cirrhosis or acute-on-chronic liver failure (ACLF).
- You are scheduled for an invasive procedure (like a biopsy or drainage).
- Your clotting is very weak: either high INR (over 2.0), very low platelets (under 30,000), or low fibrinogen (under 100).
- You are not currently bleeding and haven't had bleeding in the last 48 hours.
- You have not taken blood thinners (like aspirin or warfarin) in the past 7 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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