Fibrinogen Concentrate vs Cryoprecipitate in Liver Transplant
Treatments studied
Part of Blood & lymphatic, Digestive system, Heart & circulation clinical trials.
This trial compares two treatments to control bleeding during liver transplant surgery. One is a concentrated form of a clotting protein (fibrinogen concentrate) and the other is a blood product (cryoprecipitate). The goal is to find which works better to stop bleeding.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for a liver transplant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two treatments (prothrombin complex concentrate and fresh frozen plasma) for managing bleeding during heart surgery. It aims to find which approach works better and is safer for patients.
This trial tests whether giving a clotting protein called fibrinogen helps control bleeding during a liver transplant from a deceased donor. It may be a good option if you have certain liver conditions or lower fibrinogen levels.
This trial tests a medicine called fibrinogen concentrate (CSL511) to see if it helps control bleeding during a special surgery (cytoreductive surgery with HIPEC) for pseudomyxoma peritonei (PMP). The goal is to reduce the need for blood transfusions and improve safety.
This trial tests a treatment called INTERCEPT Fibrinogen Complex (IFC) to help control bleeding in trauma patients. It is given to patients who arrive at the hospital quickly after injury and have low fibrinogen levels.
This Phase 3 study tests whether giving fibrinogen early can improve outcomes for adults with serious trauma who are actively bleeding. The goal is to help blood clotting work better sooner and potentially reduce complications from uncontrolled bleeding.
This trial tests whether using a slightly different target on a blood-clotting test (ROTEM) can reduce the need for blood transfusions in people with liver disease who need a procedure. If you have cirrhosis or ACLF with severe clotting problems, this study may help your doctors decide how much blood product to give you before the procedure.
Hear when a new Liver Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.