Testing a natural compound with chemo for advanced colorectal cancer
Part of Cancer, Digestive system clinical trials.
This trial combines a natural substance called hydroxytyrosol (HT) with standard chemotherapy (5-FU and possibly other drugs) for people with advanced or metastatic colorectal cancer that hasn't been treated yet. The goal is to see if adding HT makes the treatment work better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have advanced (spread) or metastatic colorectal cancer confirmed by a biopsy.
- You haven't had treatment for advanced cancer yet and are eligible for 5-FU chemotherapy.
- You are in generally good health (able to care for yourself and up and about at least half the day).
- You have at least one tumor that can be measured on scans.
- You are willing to use birth control if there is any chance of pregnancy.
- You don't have serious heart, liver, kidney, or bleeding problems, and you haven't had a recent heart attack or stroke.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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