Comparing esophagitis in people with and without motility issues
Part of Digestive system clinical trials.
This study looks at patients who have a swallowing disorder called achalasia and also show signs of acid reflux damage (esophagitis). It compares these patients to those without motility problems to better understand the link.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with achalasia, a condition that makes it hard for food to move down your esophagus.
- You are eligible for a procedure called POEM (a type of endoscopic surgery) with no medical reasons against it.
- You have been found to have esophagitis (irritation or sores in your esophagus) during an endoscopy exam.
- You are not currently taking acid-reducing medication (PPI) for your reflux symptoms.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests two muscle-cutting procedures for people newly diagnosed with type 2 achalasia (a swallowing disorder). The goal is to see if a more complex myotomy works better than the standard one.
This study tracks patients with reflux, swallowing problems, or other esophageal symptoms to understand how the esophagus moves. It may help if you have heartburn, regurgitation, or related issues like cough or chest pain.
This study looks at how often acid reflux (heartburn) and esophagus irritation happen after a procedure called POEM for achalasia, and what factors make it more likely. Your answers and usual tests may help researchers understand who is at higher risk and why.
This study compares different versions of a procedure called POEM for treating achalasia, a condition where the food pipe has trouble moving food into the stomach. You may be considered if you have specific achalasia types and symptoms that are still significant despite treatment.
This trial compares two ways of making the cut during a POEM procedure (a treatment for achalasia) to see which one works better. It's for people with achalasia or similar swallowing problems who are planning to have a POEM.
This study compares a new way of doing POEM (a procedure to help you swallow) that might reduce heartburn after the procedure. It tests whether preserving a small band of muscle fibers lowers the risk of acid reflux.
Hear when a new Esophageal Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.