Chemoradiation for older adults with advanced pancreatic cancer
Part of Cancer clinical trials.
This trial tests whether a combination of chemotherapy and radiation can help older adults (70+ years) with pancreatic cancer that hasn't spread and can't be removed surgically. The goal is to control the tumor and improve quality of life without surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 70 and 85 years old and generally in good health.
- The cancer must be a type called pancreatic ductal adenocarcinoma (a common form of pancreatic cancer) that has not spread and cannot be removed with surgery, or you cannot have surgery.
- You should not have had any previous treatments for this cancer (like chemo, radiation, or other therapies).
- You should not have any other active cancer.
- Your blood counts and liver, kidney, and heart function need to be within normal ranges.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares adding radiation to chemotherapy versus chemotherapy alone after surgery for pancreatic cancer. It is for people whose cancer had certain high-risk features found during surgery, and who have not yet started additional treatment.
This trial tests a combination of targeted radiation and two oral drugs (defactinib and avutometinib) for people with advanced pancreatic cancer that hasn't spread to distant organs. It may be an option if you've already had at least 2 months of chemo and your cancer is still locally advanced or borderline resectable.
This trial tests a special, high-dose radiation treatment for pancreatic cancer that has not spread but cannot be removed with surgery. The goal is to shrink the tumor and improve control of the cancer in the abdomen.
This trial tests a combination of standard chemotherapy, MRI-guided radiation, and surgery for people with locally advanced pancreatic cancer that might be removable. The goal is to see if this approach can make more tumors resectable.
This trial is testing a new way to treat pancreatic cancer that has spread to nearby tissues but not to distant organs. It uses a tailored plan that may include chemotherapy and possibly surgery. The goal is to see if this personalized approach helps people live longer and better.
This trial tests a combination of radiation, an immunotherapy drug (adebrelimab) and a chemotherapy regimen (NALIRIFOX) before any surgery, for people with locally advanced pancreatic cancer. The goal is to shrink the tumor enough to make surgery possible, potentially improving outcomes.
Hear when a new Unresectable Locally Advanced Pancreatic Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.