Oral vs IV antibiotics for liver abscess treatment
Part of Digestive system, Infections clinical trials.
This trial compares two antibiotic treatments for liver abscess: one given through an IV (into a vein) and one taken as pills by mouth. The goal is to see if the oral treatment works just as well, which could make treatment easier and more convenient for patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a liver abscess confirmed by a CT scan or ultrasound.
- You are 18 years or older.
- You have no past history of liver abscess.
- You do not have chronic kidney disease.
- You are not allergic to metronidazole, cefixime, or beta-lactam antibiotics.
- You are not pregnant, not on blood thinners, and can take medications by mouth.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether adding a second medicine (diloxanide furoate) to the standard antibiotic (metronidazole) helps people recover from an amoebic liver abscess. If you have this condition and are otherwise healthy, this treatment might improve your recovery.
This study looks at how patients with liver abscesses (pus pockets in the liver) respond to treatment. It helps doctors understand which treatments work best and improves care for future patients.
This study compares two strong antibiotics to see which one works better for people with liver failure who get a hospital-acquired infection caused by resistant bacteria. The two drugs are ceftazidime-avibactam and a higher dose of meropenem given as an extended infusion.
This trial looks at whether continuing treatment for a bacterial brain abscess using partially oral antibiotics works as well as the usual approach. It may help people who have already had 14 days of antibiotic treatment and are stable enough to take medicines by mouth.
This trial tests whether switching from IV to oral antibiotics is just as effective for treating Gram-negative bloodstream infections. If you qualify, you may receive either continued IV antibiotics or switch to pills, with follow-up on your recovery and quality of life.
This trial compares starting antibiotics through a vein (IV) to taking them by mouth for common infections like pneumonia, urinary tract infections, or skin infections (cellulitis). The goal is to see if oral antibiotics work just as well without the need for an IV line.
Hear when a new Liver Abscess trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.