Study of JP-1366 tablets for heartburn and acid reflux
Part of Digestive system clinical trials.
This trial tests a new medication, JP-1366, for people with reflux esophagitis (damage to the esophagus from stomach acid). It aims to see if the drug is safe and effective at healing the esophagus and relieving symptoms like heartburn and regurgitation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have had heartburn or regurgitation in the last 7 days, or a recent diagnosis of reflux esophagitis via endoscopy (a camera test of your esophagus).
- You are willing to use effective birth control during the study (if applicable).
- You do not have certain other gastrointestinal conditions, such as Barrett’s esophagus, active ulcers, or a history of surgery on your stomach or esophagus.
- You have not used strong acid-reducing medications (like Nexium or omeprazole) in the last 2 weeks, or certain other acid blockers in the last week.
- You do not have serious heart, liver, kidney, or bleeding problems that could increase risk.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new medicine called anaprazole for people with moderate to severe reflux esophagitis (chronic heartburn and damage to the food pipe). It compares anaprazole to a standard treatment to see which works better and is safer.
This trial tests a new medicine, JP-1366, for people with non-erosive GERD (heartburn and acid reflux without visible damage to the esophagus). The goal is to see if it helps control symptoms better than a placebo.
This trial tests a new medicine (JP-1366) to see if it can keep the esophagus healed in people who have been treated for erosive esophagitis. You may join if you are an adult with healed erosive esophagitis and have taken standard acid-blocking medication for at least 4 weeks.
This study tests a new topical treatment for people with chronic heartburn and acid regurgitation who don't have erosions (damage) in their esophagus. The treatment is applied directly to the affected area and may help relieve symptoms without taking daily pills.
This study looks at how following specific diet and behavior changes affects symptoms of acid reflux (heartburn/regurgitation) in everyday life. It may help you understand what lifestyle steps improve reflux and how symptoms change over time.
This trial tests a new drug called JP-1366 to see if it can prevent stomach ulcers caused by long-term NSAID use (like ibuprofen or naproxen) for conditions such as arthritis. It may be a good fit if you need to take NSAIDs for at least 24 weeks and have a higher risk of ulcers.
Hear when a new Reflux Esophagitis (RE) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.