Medication to prevent acid reflux from returning
Treatments studied
Part of Digestive system clinical trials.
This trial tests a new medication (JP-1366) to see if it helps prevent acid reflux damage from coming back. You may join if you have had erosive esophagitis that healed after treatment, and you are currently doing well without other serious conditions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 19 to 75 years old.
- You have been diagnosed with erosive esophagitis, a type of acid reflux that damages the esophagus lining.
- You have taken a medication for acid reflux, like a PPI or P-CAB, for at least 4 weeks.
- You have no signs of serious conditions like bleeding, weight loss, or difficulty swallowing.
- You have no other conditions of the esophagus such as Barrett's esophagus or narrowing.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests an investigational medication called JP-1366 for people with non-erosive GERD, a condition where acid reflux causes heartburn and regurgitation but no visible damage to the esophagus. The goal is to see if this new treatment can safely reduce symptoms better than a placebo.
This trial tests a new medication, JP-1366, for people with reflux esophagitis (damage to the esophagus from stomach acid). It aims to see if the drug is safe and effective at healing the esophagus and relieving symptoms like heartburn and regurgitation.
This study tests a new medicine to keep acid reflux from damaging the esophagus again after it has healed. It may help prevent symptoms like heartburn from coming back.
This study tests a new topical treatment for people with chronic heartburn and acid regurgitation who don't have erosions (damage) in their esophagus. The treatment is applied directly to the affected area and may help relieve symptoms without taking daily pills.
This trial tests a new way to treat GERD (chronic acid reflux) using a tiny camera and a device that delivers a gentle heat treatment (argon plasma coagulation) to the area where the stomach meets the esophagus. It's compared to a 'sham' procedure (you won't know which you get) to see if it stops acid from backing up better than medicine alone.
This trial tests a new endoscopic procedure called anti-reflux mucosal ablation therapy to reduce acid reflux in people who still have symptoms despite taking acid-reducing medication. The goal is to see if this treatment helps improve heartburn and related symptoms.
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