Clin2
NCT06852456Possibly a fitNot yet recruiting

QL1706 plus chemo before surgery for esophageal cancer

Resectable Locally Advanced Esophageal Squamous Cell Carcinoma

Treatments studied

Part of Cancer clinical trials.

This trial tests adding an immunotherapy drug (QL1706) to standard chemotherapy before surgery for a certain type of esophageal cancer. The goal is to see if the combination works better than chemotherapy alone at shrinking the tumor and improving surgery outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
30 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have been diagnosed with squamous cell cancer of the esophagus that is locally advanced but can still be surgically removed.
  • You have not had any prior treatment for this cancer.
  • You are in good physical condition (able to care for yourself and do light activities).
  • Your doctor expects to be able to remove all visible cancer during surgery after the initial treatment.
  • You do not have major bleeding issues, significant tumor invasion into nearby organs, or uncontrolled fluid buildup in your body.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06908382Recruiting· Phase 2
Neoadjuvant QL1706 therapy for esophageal cancer before surgery

This trial tests a new immunotherapy drug, QL1706, given before surgery for esophageal squamous cell cancer. The goal is to see if it helps shrink tumors and improve outcomes for patients who are healthy enough for the treatment.

Jinan, Shandong
NCT07530549Not yet recruiting· Phase 2
New treatment for advanced esophageal cancer after initial therapy fails

This study tests a new treatment approach for patients with advanced esophageal cancer whose disease progressed or didn't respond to initial chemotherapy and immunotherapy. The goal is to see if this new treatment can help shrink tumors and improve outcomes for patients who cannot have surgery.

NCT07533305Not yet recruiting· Phase 2
New drug with chemotherapy for advanced esophageal cancer

This trial tests whether adding a new drug called QL1706 to standard chemotherapy (two common cancer drugs) works better for advanced esophageal cancer that can't be surgically removed. The goal is to see if this combination helps patients live longer and controls the cancer better than chemotherapy alone.

NCT07490002Not yet recruiting· Phase 2
Chemo-immunotherapy before surgery for esophageal cancer

This trial tests a combination of two immunotherapy drugs, chemotherapy, and lenvatinib before surgery to treat esophageal squamous cell carcinoma that hasn't spread and can be removed. It aims to see if this approach can improve outcomes for patients with stage II to IVa disease.

NCT07283991Not yet recruiting· Phase 2
Experimental therapy plus chemo for borderline resectable esophageal cancer

This trial tests a new drug called QL1706 combined with standard chemotherapy to see if it can shrink esophageal tumors that are hard to remove with surgery alone. It’s for people who haven’t had any treatment yet and are well enough for daily activities.

NCT07617818Not yet recruiting· Phase 2
QL1706 plus chemotherapy before cervical cancer surgery

This trial tests whether adding a new immunotherapy drug called QL1706 to standard chemotherapy before surgery can help treat early-stage cervical cancer better. The goal is to shrink tumors and improve outcomes for patients who haven't had immune therapy before.

Hear when a new Resectable Locally Advanced Esophageal Squamous Cell Carcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.