Clin2
NCT06856278Possibly a fitNot yet recruiting

CAR-NK plus PD-1 for anaplastic thyroid cancer

Anaplastic Throid Carcinoma

Part of Cancer clinical trials.

This trial tests a new treatment for anaplastic thyroid cancer that combines two immune-based therapies: NKG2D CAR-NK cells (a type of white blood cell engineered to attack cancer) and a PD-1 inhibitor (a drug that helps the immune system fight cancer). The goal is to see if this combination is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
30 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have been diagnosed with anaplastic thyroid cancer and have at least one tumor that can be measured and is at least 1 cm in size.
  • Your liver and kidney function are good enough to handle the treatment.
  • You are able to cooperate with the treatment plan and follow-up visits.
  • You do not have other serious health conditions, including other types of cancer.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07777536Recruiting· Phase 2
Radiation for anaplastic and poorly differentiated thyroid cancer

This study is comparing two different ways of giving radiation therapy for anaplastic and poorly differentiated thyroid cancer. The goal is to see which method is more effective in treating the cancer.

Shanghai, Shanghai Municipality
NCT06816823Recruiting· Phase 1
CAR-NK Cells for Advanced Pancreatic Cancer

This trial tests a new type of immunotherapy called CAR-NK cells (CL-NK-001) for patients with advanced pancreatic cancer that has a specific marker (eGR1). The goal is to see if these specially grown natural killer cells can attack the cancer after standard treatments have stopped working.

Shanghai
NCT07164560Recruiting· Phase 1
CAR-NK cell therapy for relapsed T-cell lymphoma

This trial tests a new treatment using immune cells (CAR-NK) made from donated cord blood. These cells are designed to find and attack T-cell lymphoma that has come back or not responded to other treatments. The goal is to see if this approach is safe and effective.

Hangzhou, Zhejiang
NCT06374602Recruiting· Phase 2
Pembrolizumab and lenvatinib for anaplastic thyroid cancer

This trial tests a combination of two drugs, pembrolizumab and lenvatinib, for people with a rare and aggressive thyroid cancer that cannot be removed by surgery. The goal is to see if this treatment can shrink the tumor or slow its growth.

Saint Petersburg
NCT07510828Recruiting· Phase 1/Phase 2
CAR-NK cells for advanced solid tumors

This trial tests whether specially engineered NK cells can find and attack your type of cancer. It is for people with advanced solid tumors that haven't responded to standard treatments.

Shenzhen, Guangdong
NCT05528341Recruiting· Phase 1
CAR NK cell treatment trial for solid tumor cancers

This Phase 1 study tests a lab-made immune cell treatment (CAR-NK92 cells) for people with solid tumors that have not responded to earlier treatments. The goal is to see how safe it is and whether it can shrink tumors or help control cancer.

Xinxiang, Henan

Hear when a new Anaplastic Throid Carcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.