Precision antibiotic dosing for appendix removal
Treatments studied
Part of Digestive system, Infections clinical trials.
This trial tests a more precise way to give antibiotics before and after appendix removal surgery. It aims to find the best dose for each patient to reduce infections and side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with acute appendicitis and are planning to have your appendix removed at the University of Michigan.
- You are not a prisoner.
- You are not pregnant.
- A CT scan did not show a perforated appendix or an abscess (a pocket of infection).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares whether you need antibiotics after laparoscopic surgery for a complicated, “localized” appendix infection. It aims to find the safest, most effective antibiotic approach after surgery.
This study tests whether taking antibiotics by mouth at home works as well as placebo (a dummy pill) to treat uncomplicated appendicitis. It might help you avoid surgery and recover without a hospital stay.
This trial tests whether patients who have straightforward appendix removal surgery need antibiotics for just 1 day or 5 days afterward. The goal is to find the shortest safe antibiotic course that prevents infection.
This trial tests whether taking antibiotics alone can treat acute uncomplicated appendicitis, compared with a placebo. If antibiotics work, it may help some people avoid surgery or reduce treatment intensity.
This study tests whether children with early appendicitis (inflammation of the appendix) can be treated safely with antibiotics instead of surgery. Researchers want to see if antibiotics work as well as surgery while avoiding the risks of an operation.
This trial tests whether giving antibiotics after surgery helps people with a perforated appendix recover better. If you are having an appendectomy and your surgeon finds a complicated appendix, you may be able to join.
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