Antibiotics versus placebo for uncomplicated appendicitis
Treatments studied
Part of Digestive system, Infections clinical trials.
This trial tests whether taking antibiotics alone can treat acute uncomplicated appendicitis, compared with a placebo. If antibiotics work, it may help some people avoid surgery or reduce treatment intensity.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- Your appendicitis was confirmed by a CT scan as “uncomplicated.”
- You can understand the study and sign informed consent.
- You are not pregnant and not breastfeeding.
- You do not have an allergy to contrast dye/iodine used for CT scans.
- You are not allergic to antibiotics and have no reason you cannot take antibiotics.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two treatments for uncomplicated appendicitis: taking antibiotics or having surgery to remove the appendix. It aims to see which option works better and respects your choice.
This trial looks at whether different ways of diagnosing appendicitis (like CT scans) are accurate. It's for people who already had surgery to remove their appendix and want to help doctors learn more.
This trial compares taking antibiotic pills at home versus a placebo (sugar pill) for treating mild appendicitis. If successful, it could mean avoiding surgery for many patients.
This study looks at why some people with uncomplicated appendicitis get better with antibiotics alone, while others still need surgery. If you join, researchers will track your treatment to find patterns that help predict success, aiming to help more patients avoid surgery in the future.
This study compares two common ways to treat a simple (uncomplicated) appendix problem in children: using antibiotics versus having surgery to remove the appendix. The goal is to see which approach works better and helps children recover faster.
This trial tests a newer, less invasive procedure called ERAT against standard laparoscopic appendectomy for adults with a first episode of uncomplicated appendicitis. The goal is to see which approach works better with fewer risks.
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