Oral antibiotics versus placebo for mild appendicitis
Treatments studied
Part of Digestive system, Infections clinical trials.
This trial compares taking antibiotic pills at home versus a placebo (sugar pill) for treating mild appendicitis. If successful, it could mean avoiding surgery for many patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- A CT scan shows your appendix is inflamed but not burst or blocked.
- You do not have a fever above 38°C (100.4°F).
- You have no other serious medical conditions (like cancer or a weakened immune system).
- You are not allergic to contrast dye or the antibiotic moxifloxacin.
- You have no heart rhythm problems or take medicines that affect heart rhythm.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests whether taking antibiotics alone can treat acute uncomplicated appendicitis, compared with a placebo. If antibiotics work, it may help some people avoid surgery or reduce treatment intensity.
This trial compares two treatments for uncomplicated appendicitis: taking antibiotics or having surgery to remove the appendix. It aims to see which option works better and respects your choice.
This study tests whether antibiotics are necessary for mild diverticulitis or if a placebo works just as well. Participants are treated in the emergency department and followed using a smartphone app.
This study compares two common ways to treat a simple (uncomplicated) appendix problem in children: using antibiotics versus having surgery to remove the appendix. The goal is to see which approach works better and helps children recover faster.
This study looks at why some people with uncomplicated appendicitis get better with antibiotics alone, while others still need surgery. If you join, researchers will track your treatment to find patterns that help predict success, aiming to help more patients avoid surgery in the future.
This trial tests whether rinsing the belly with antibiotics during appendix removal surgery can lower the chance of a pocket of infection (abscess) forming afterward. It may help people with a more severe type of appendicitis called complicated appendicitis.
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