Clin2
NCT06865105Possibly a fitRecruiting

Targeted treatments for active psoriatic arthritis

Psoriatic Arthritis

Treatments studied

Part of Bones, joints & muscles, Skin clinical trials.

This study tests targeted medications for people with active psoriatic arthritis (PsA) who have already tried 1 or 2 other advanced treatments without success or couldn't tolerate them. The goal is to see if these newer options can better control joint pain and skin symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
120 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with psoriatic arthritis for at least 6 months
  • You currently have at least 3 tender and 3 swollen joints
  • You have active psoriasis or a clear history of it
  • You have tried 1 or 2 advanced medications (biologics or targeted pills) for PsA and they didn't work well or caused side effects
  • You do not have HIV, active hepatitis B or C, or active tuberculosis
  • You do not have another inflammatory joint condition like rheumatoid arthritis or fibromyalgia

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06764693Recruiting
Study on treatment with Risankizumab for psoriatic arthritis

This study tests how well a medicine called Risankizumab works for people with psoriatic arthritis. It is for adults who have had symptoms for at least 6 months and have not had enough help from at least one other arthritis medicine.

Quilmes, Buenos Aires
NCT06671483Recruiting· Phase 3
Zasocitinib for psoriatic arthritis without prior biologic use

This trial tests an oral medication called zasocitinib for adults with psoriatic arthritis who have not tried biologic medicines before. It aims to see if the drug can improve joint pain, swelling, and skin symptoms.

Chandler, Arizona
NCT07295509Recruiting· Phase 2/Phase 3
Testing picankibart for active psoriatic arthritis

This trial tests a new drug called picankibart to see if it helps people with active psoriatic arthritis who haven't gotten enough relief from standard treatments like NSAIDs or non-biologic DMARDs. It may be an option if you have at least 3 tender and 3 swollen joints and active or past plaque psoriasis.

Hangzhou, Zhejiang
NCT05291819Recruiting
Imaging-guided vs standard treatment for psoriatic arthritis

This study compares two “treat-to-target” strategies for psoriatic arthritis. One strategy uses imaging to guide treatment changes, and the other uses standard clinic assessments, to see which approach controls symptoms more effectively.

Ålesund
NCT05954364Recruiting
Study of advanced treatments for psoriatic arthritis based on sex and gender

This study looks at how well advanced treatments work for people with psoriatic arthritis, and whether results differ for sex and gender. You may be eligible if your psoriatic arthritis is active and you are planning to start an advanced treatment for symptoms in the joints and surrounding areas.

Toronto, Ontario
NCT05669833Recruiting· Phase 3
Guselkumab versus golimumab for active psoriatic arthritis

This Phase 3 study compares two biologic medicines—guselkumab and golimumab—to see which works better for people with active psoriatic arthritis. It is designed for people whose psoriatic arthritis did not respond well to a prior “TNF-blocking” medicine (or lost response).

Loxahatchee Groves, Florida

Hear when a new Psoriatic Arthritis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.