Estrogen and heart health in women with early menopause
Part of Hormones & metabolism, Women’s health & pregnancy clinical trials.
This study looks at how estrogen therapy affects heart health in women with primary ovarian insufficiency (early menopause). Participants will take a standard estrogen patch and progesterone pill, and researchers will monitor their heart function over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 30 to 40.
- If you have primary ovarian insufficiency (POI), you must have been diagnosed within the last 6 months and be ready to start a specific estrogen patch and progesterone pill treatment.
- If you do not have POI, you must have regular periods every 21–35 days.
- You have not taken any estrogen replacement therapy before.
- You have not used hormone therapy (like contraception or testosterone) in the last 6 months.
- You do not have certain health conditions such as a history of blood clots, stroke, breast cancer, severe liver disease, or uncontrolled high blood pressure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how estrogen levels affect heart health in women after menopause. You may be asked to wear an estrogen patch to see if it helps your heart and blood vessels.
This study looks at how different menopause hormone therapies affect heart health in women who are at increased risk for heart problems. It aims to find which treatments are safest and most effective for women going through menopause.
This study tests whether menopausal hormone therapy can improve brain and heart health in women going through menopause. It looks at how treatment affects blood vessels and thinking skills.
This study looks at how menopausal hormone therapy might affect the heart's pumping ability. It may help women who are naturally entering menopause understand if hormone therapy can protect their heart health.
This study looks at how hormones affect heart health and metabolism in women who are having their ovaries removed (for non-cancer reasons). It will help researchers understand the changes that happen after surgery and how to better manage health during this transition.
This study looks at how temporarily stopping ovarian function affects weight, body fat, and blood vessel health in premenopausal women. If you qualify, you might help researchers understand the risks and benefits of short-term estrogen suppression.
Hear when a new Primary Ovarian Insufficiency trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.