POEM procedure for swallowing problems after anti-reflux surgery
Part of Digestive system, Ear, nose & throat clinical trials.
This trial tests a new endoscopic procedure called POEM to help people who still have trouble swallowing after having had a fundoplication surgery for acid reflux. It may offer a way to improve swallowing without more traditional surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You had a fundoplication surgery for acid reflux (Nissen, Toupet, or Dor) within the last 10 years.
- You have had trouble swallowing for more than 6 months that is not helped by standard treatments.
- You have severe swallowing difficulty (measured by a score your doctor can check).
- An X-ray shows a narrowing at the lower esophagus and food or liquid getting stuck, and a special probe confirms the narrowing.
- You have tried at least one prokinetic medication (a drug that helps the stomach empty).
- You have not had a previous myotomy (cutting of the esophagus muscle).
- You do not have other causes for the swallowing problem, such as achalasia, stricture, or cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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