POEM for swallowing problems after reflux surgery
Part of Digestive system, Ear, nose & throat clinical trials.
This trial tests a procedure called POEM (a tube-based surgery to cut the tight muscle in your esophagus) to fix swallowing problems that happen after a common reflux surgery. It's for people who have had a fundoplication and now have trouble swallowing for more than 6 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a reflux surgery (fundoplication) within the last 10 years.
- You have had severe trouble swallowing for more than 6 months that hasn't gotten better with medicine.
- X-ray and special tests show your esophagus is narrowed at the bottom and food gets stuck.
- You haven't had a previous myotomy (cutting of the esophagus muscle) for this or other reasons.
- You have no active ulcers, severe heartburn, or other serious conditions like advanced liver disease or cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at a procedure called POEM, followed by prolonged stretching, to treat swallowing problems caused by specific esophagus muscle disorders. If you have the right diagnosis and can safely have an endoscopy, this may help improve how well food moves through your esophagus.
This trial studies how well POEM and other endoscopy-based (through-the mouth) treatments work for conditions like acid reflux, achalasia (trouble moving food), and Barrett’s esophagus. It may help doctors compare outcomes and choose the safest, most effective procedure for your situation.
This study compares a new way of doing POEM (a procedure to help you swallow) that might reduce heartburn after the procedure. It tests whether preserving a small band of muscle fibers lowers the risk of acid reflux.
This study compares different versions of a procedure called POEM for treating achalasia, a condition where the food pipe has trouble moving food into the stomach. You may be considered if you have specific achalasia types and symptoms that are still significant despite treatment.
This study looks at how useful the POEM procedure is for people with gut “motility” (trouble moving food through the digestive tract). If you’re already scheduled for POEM, your team will also track how well it helps and whether it’s practical in real care.
This trial looks at people who had a procedure called POEM for achalasia and want to understand outcomes after that treatment. If you’re an adult and already had POEM for achalasia, you may be able to join.
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