Clin2
NCT06872580Possibly a fitNot yet recruiting

QLS1209 for advanced solid tumors with specific genetic changes

Advanced Solid Tumor

Part of Cancer clinical trials.

This trial tests an experimental drug (QLS1209) for advanced solid tumors that have not responded to standard treatments or when no standard treatment exists. The study looks for tumors with certain genetic changes (in CCNE1, FBXW7, or PPP2R1A) and may help guide future treatment options.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
149 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 or older.
  • You must have an advanced solid tumor that has failed standard treatment or for which no standard treatment exists.
  • Your tumor or blood must show a specific genetic change: either CCNE1 amplification, or a mutation in FBXW7 or PPP2R1A.
  • You must have at least one tumor that can be measured or seen on scans.
  • You must not have had certain cancer treatments (like chemotherapy, targeted therapy, or radiation) within 4 weeks (or 2-8 weeks for some types) before starting the study drug.
  • You must not have untreated or worsening brain metastases, or other serious lung, stomach, or health conditions.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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