Mannitol's effect on propofol levels during brain tumor surgery
Treatments studied
This trial studies how mannitol, a medicine to reduce brain swelling, affects the levels of propofol (an anesthesia drug) in your blood during brain tumor surgery. It may help doctors adjust anesthesia doses more safely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are classified as ASA II, meaning you have mild systemic disease (like well-controlled diabetes or high blood pressure).
- You are having surgery for a brain tumor located in the upper part of your brain (supratentorial).
- You are able to receive mannitol, a medicine used during brain surgery.
- You will receive total intravenous anesthesia (anesthesia given only through an IV line).
- You do not have chronic kidney failure, sepsis, or multiorgan failure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two types of anesthesia (gas vs. IV) during brain tumor surgery to see which one better protects the brain and helps with thinking and memory after the operation.
This study tests how different blood pressure medicines affect blood flow to the brain and other organs during anesthesia for brain tumor surgery. It aims to find the safest way to keep your brain healthy while you are asleep.
This trial tests a new pain management plan for people having brain tumor surgery. The goal is to see if combining different pain medicines before, during, and after surgery can reduce pain and improve recovery.
This trial compares two ways of giving anesthesia during planned brain surgery on the upper part of the brain. It tests if using a computer-controlled system to deliver the anesthesia drugs is better than manually adjusting them.
This study looks at whether brain tumor surgery affects the risk of confusion and disorientation (delirium) after the operation. It may help doctors better prevent and manage post-surgery delirium in patients like you.
This trial tests a new way of giving the anesthetic propofol to keep your blood pressure more stable during surgery. It may help reduce side effects like dizziness or fainting after the procedure.
Hear when a new Mannitol Adverse Reaction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.