Mannitol's effect on propofol levels during brain tumor surgery
Treatments studied
This trial studies how mannitol, a medicine to reduce brain swelling, affects the levels of propofol (an anesthesia drug) in your blood during brain tumor surgery. It may help doctors adjust anesthesia doses more safely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are classified as ASA II, meaning you have mild systemic disease (like well-controlled diabetes or high blood pressure).
- You are having surgery for a brain tumor located in the upper part of your brain (supratentorial).
- You are able to receive mannitol, a medicine used during brain surgery.
- You will receive total intravenous anesthesia (anesthesia given only through an IV line).
- You do not have chronic kidney failure, sepsis, or multiorgan failure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two anesthetic drugs (ciprofol and propofol) to see which one is safer for the brain during surgery to remove a brain tumor. It focuses on patients whose tumors cause significant brain swelling or pressure.
This trial tests a combination of pain medicines given before, during, and after brain surgery to see if it can reduce pain and improve recovery. If you are having surgery to remove a tumor in the upper part of your brain, this study may help manage your pain more effectively.
This trial compares two types of anesthesia (gas vs. IV) during brain tumor surgery to see which one better protects the brain and helps with thinking and memory after the operation.
This study tests how different blood pressure medicines affect blood flow to the brain and other organs during anesthesia for brain tumor surgery. It aims to find the safest way to keep your brain healthy while you are asleep.
This trial tests a new way of giving the anesthetic propofol to keep your blood pressure more stable during surgery. It may help reduce side effects like dizziness or fainting after the procedure.
This study tests whether using a non-invasive monitor to guide fluid and medication during planned brain surgery helps keep your blood pressure and heart rate stable. It may help reduce complications during and after surgery.
Hear when a new Mannitol Adverse Reaction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.