Dapagliflozin for kids with genetic kidney disease and protein in urine
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests if dapagliflozin, a medication that lowers blood sugar and protects the kidneys, can reduce protein in the urine of children with inherited kidney disease. It may help preserve kidney function when added to standard blood pressure medication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a confirmed genetic kidney disease (tested by genetic testing or diagnosed by a doctor).
- Your urine must have more than a small amount of protein (over 0.2 grams in 24 hours or a specific ratio).
- Kidney function must be at least 60% of normal (measured by a blood test).
- You must be on a stable dose of a certain blood pressure medicine (ACE inhibitor or ARB) for at least 4 weeks.
- You cannot have used steroids or other immune-suppressing medicines, or another drug called SGLT2 inhibitor, in the last 4 weeks.
- You cannot have diabetes, a current urinary tract infection, very low blood pressure, or a history of organ transplant or cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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