Immune drugs combined with chidamide for HIV cure
Treatments studied
Part of Infections clinical trials.
This trial tests whether combining immune-boosting drugs with chidamide (a medication that may wake up hidden HIV) can help your body control HIV without daily antiretroviral therapy. It aims to achieve a 'functional cure,' meaning the virus stays suppressed even after stopping regular HIV meds.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been on HIV treatment (ART) for at least 2 years.
- Your HIV viral load has been undetectable (below 50 copies/mL) for at least 1 year.
- Your CD4 count is 350 or higher.
- You are generally healthy with a BMI between 18 and 35.
- You have not had any serious illness in the past 8 weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether giving two experimental drugs together can help your immune system find and destroy hidden HIV cells. It aims to see if this approach can reduce the amount of virus in your body even while you're on your regular HIV medications.
This study tests a new combination of two drugs to see if they can reduce the 'hidden' HIV that stays in your body even when you're on regular HIV treatment. The goal is to work toward a cure, not just control.
This study tests whether combining two or more investigational drugs that can activate the hidden HIV reservoir in your body might help eliminate it. The goal is to see if this approach is safe and could help lead to a cure for HIV.
This trial tests a new combination of three medications, lenacapavir, teropavimab, and zinlirvimab, for people with HIV who currently have undetectable virus levels on a stable oral treatment. The goal is to see if these drugs can keep the virus suppressed, possibly allowing a simpler treatment plan.
This study tests whether combining two drugs, ibalizumab and chidamide, can reduce the hidden HIV in your body. It aims to see if this combination is safe and might help control HIV better.
This trial tests a combination of an HIV vaccine and a new antibody treatment (GS-2872) to see if it can help control HIV without daily pills. It is for people with well-controlled HIV who are looking for ways to reduce their dependence on antiretroviral therapy.
Hear when a new HIV-1-infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.