Clin2
NCT06911489Possibly a fitRecruiting

Safety trial of a new targeted therapy for advanced solid tumors

Solid Tumor Malignancy

Part of Cancer clinical trials.

This trial tests a new drug, NRT6020, that targets a protein called FAP found on many solid tumors. It aims to see if the drug is safe and how it works in people with advanced solid tumors that have not responded to other treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
132 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You must be between 18 and 80 years old
  • You must have an advanced solid tumor that has been confirmed by a biopsy or other test
  • You must have at least one tumor that can be measured on a scan
  • You must have good organ function and be able to care for yourself (ECOG score of 0 or 1)
  • You must not have brain tumors or brain metastases
  • You must agree to use effective birth control during the trial and for 12 months after

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07439120Recruiting· Early Phase 1
Testing a new radioactive drug for advanced solid tumors

This trial tests a new radioactive drug called 68Ga/177Lu-BRP-020063 in people with advanced solid tumors, especially bladder or breast cancer. The drug seeks out Nectin-4 on cancer cells, helping doctors see and potentially treat the tumors. The goal is to check that the drug is safe and tolerable.

Shanghai
NCT04939610Recruiting· Phase 1/Phase 2
Studying a targeted radiation drug for advanced solid tumors

This trial tests how safe and effective a targeted radiation medicine (177Lu-FAP-2286) is for people with advanced solid cancers that have limited treatment options. It may help by delivering radiation directly to cancer-related targets and shrinking tumors.

Birmingham, Alabama
NCT06197139Recruiting· Phase 1
Study of a new targeted radiation therapy for advanced solid tumors

This trial tests an investigational drug called [177Lu]Lu-XT117, which delivers a small dose of radiation directly to cancer cells that have a specific protein called FAP. It is for people with advanced solid tumors who have run out of standard treatment options or cannot tolerate them.

Guangzhou
NCT07639970Not yet recruiting· Early Phase 1
Testing a new targeted treatment for solid tumors

This trial tests an experimental drug that targets tumors with a special protein detected by a PET scan. It may help treat certain cancers like breast, head and neck, pancreatic, or brain cancers that have grown despite prior treatment.

NCT07808177Recruiting· Early Phase 1
Study of a targeted radiation drug for advanced solid tumors

This trial is testing an investigational drug called 177Lu-FAP-VG1 for people with advanced solid tumors that have stopped responding to standard therapy. The drug is a type of radiation therapy that targets a protein called FAP, which is found on many cancer cells, to try to shrink the tumor and slow the cancer's growth.

Jinan, Shandong
NCT07707999Not yet recruiting· Early Phase 1
Imaging solid tumors with a targeted tracer

This trial tests a special imaging technique that may help doctors see and stage solid tumors more precisely. It uses a targeted radioactive tracer to highlight cancer cells during PET and SPECT scans, which could help plan better treatment.

Wuhan, Hubei

Hear when a new Solid Tumor Malignancy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.