Clin2
NCT06916325Likely a fitNot yet recruiting

Preserving donor livers with eXVIVO before transplant

Liver Transplant SurgeryLiver Transplantation

Part of Digestive system clinical trials.

This trial tests a new way to preserve donated livers with a machine called eXVIVO before transplant. It is for adults receiving their first liver transplant and aims to see if this preservation method improves outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
215 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must be listed for your first liver transplant on the UNOS waiting list.
  • If you have liver cancer (HCC), the tumor must meet Milan criteria or be reduced to that size before transplant.
  • You cannot need a ventilator or heart support machines.
  • You cannot be pregnant or receiving other organ transplants at the same time.
  • You cannot be in another trial with an experimental drug or device.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05680246Recruiting
Study of long-term outcomes after special donor-liver preservation

This study looks at how well people do in the long run after liver transplant using donor livers that were preserved in a specific machine called DHOPE for more than 4 hours. It may help doctors understand whether this preservation method leads to better transplant outcomes over time.

Groningen
NCT06717919Recruiting· Phase 4
Testing HOPE treatment to prevent liver cancer return after transplant

This study tests a special way of preserving donated livers, called HOPE, to see if it lowers the chance of liver cancer coming back after a liver transplant. If you have liver cancer and are waiting for a transplant, this trial might be an option for you.

New York, New York
NCT06371924Recruiting
Machine perfusion for livers from donation after circulatory death

This study tests a new way to preserve donated livers (called machine perfusion) after they are recovered from donors who died from circulatory causes. It aims to see if this method helps the liver work better before transplant.

Birmingham
NCT07585890Recruiting
Liver Transplant Outcomes With Machine Preservation in Europe

This study collects information about how livers do after transplantation when they've been preserved using machine perfusion—a technique that keeps donor livers in better condition before surgery. Researchers want to understand which preservation methods work best to improve transplant success across Europe.

Vienna
NCT07651748Enrolling by invitation· Phase 1/Phase 2
Testing Secretin to Improve Donated Liver Quality

This trial tests whether adding a hormone called secretin to a machine that preserves donated livers outside the body can improve liver quality and transplant outcomes. You may qualify if you're an adult receiving a standard deceased-donor liver transplant that needs special preservation techniques.

Rotterdam, South Holland
NCT06874296Recruiting
Testing machine perfusion for declined livers to shorten transplant wait time

This trial tests whether using a machine to keep donated livers healthy (normothermic machine perfusion) can allow more people to receive a transplant sooner. It is for patients who are already on the waiting list for a liver and have a moderately severe MELD score (25 or less).

Hamburg, Free and Hanseatic City of Hamburg

Hear when a new Liver Transplant Surgery trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.