Clin2
NCT07585890Likely a fitRecruiting

Liver Transplant Outcomes With Machine Preservation in Europe

End-stage Liver Disease (ESLD)Acute Liver FailureLiver CirrhosisLiver Transplantation

Part of Digestive system clinical trials.

This study collects information about how livers do after transplantation when they've been preserved using machine perfusion—a technique that keeps donor livers in better condition before surgery. Researchers want to understand which preservation methods work best to improve transplant success across Europe.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
10,000 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You received a liver transplant from a deceased donor (not a living donor)
  • You were at least 18 years old when you had your transplant
  • Your donor's liver was preserved using machine perfusion or standard cold storage
  • Your transplant was part of routine clinical care, not an experimental research study comparing different preservation methods
  • At least 12 months have passed since your liver transplant

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06371924Recruiting
Machine perfusion for livers from donation after circulatory death

This study tests a new way to preserve donated livers (called machine perfusion) after they are recovered from donors who died from circulatory causes. It aims to see if this method helps the liver work better before transplant.

Birmingham
NCT06874296Recruiting
Testing machine perfusion for declined livers to shorten transplant wait time

This trial tests whether using a machine to keep donated livers healthy (normothermic machine perfusion) can allow more people to receive a transplant sooner. It is for patients who are already on the waiting list for a liver and have a moderately severe MELD score (25 or less).

Hamburg, Free and Hanseatic City of Hamburg
NCT06916325Not yet recruiting
Preserving donor livers with eXVIVO before transplant

This trial tests a new way to preserve donated livers with a machine called eXVIVO before transplant. It is for adults receiving their first liver transplant and aims to see if this preservation method improves outcomes.

NCT07651748Enrolling by invitation· Phase 1/Phase 2
Testing Secretin to Improve Donated Liver Quality

This trial tests whether adding a hormone called secretin to a machine that preserves donated livers outside the body can improve liver quality and transplant outcomes. You may qualify if you're an adult receiving a standard deceased-donor liver transplant that needs special preservation techniques.

Rotterdam, South Holland
NCT05680246Recruiting
Study of long-term outcomes after special donor-liver preservation

This study looks at how well people do in the long run after liver transplant using donor livers that were preserved in a specific machine called DHOPE for more than 4 hours. It may help doctors understand whether this preservation method leads to better transplant outcomes over time.

Groningen
NCT06418165Recruiting
Cooled oxygenated machine perfusion for liver transplant

This study tests a new way to preserve donated livers using a machine that keeps the organ cool and oxygenated before transplant. It may help improve how well the liver works after the surgery.

Vienna

Hear when a new Acute Liver Failure trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.